Last update
5/18/2025

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 1 Nugget
Amount Per Serving
%DV
Vitamin B12 (as methylcobalamin)
5,000 mcg
208,333%

Top Medical Research Studies

7
Vitamin B12 ineffective alone
We explored how vitamin B12 might serve as a protective agent against food poisoning, particularly from pyrrolizidine alkaloids found in tansy ragwort. The study assessed various dietary supplements alongside vitamin B12, including butylated hydroxyanisole and cysteine, on rats exposed to these toxic compounds. While the combination of these agents did enhance the survival time of the rats significantly, the added vitamin B12 did not show any notable improvement in outcomes when used alone.

In examining our findings, it became clear that B12's contribution in isolation lacked evidence of effectiveness against PA poisoning. The results indicated that while certain combinations could be beneficial, vitamin B12 alone did not alter the susceptibility to the toxic effects observed from the chronic consumption of tansy ragwort. This highlights the need for further investigation into the role of B12 and how it interacts with other treatments.
Read More

Most Useful Reviews

9
Symptoms disappeared
1 people found this helpful
Best B12 for vegans and raw foodists! After switching to a vegan diet, I had a strong shortage of B12. Remarkably, after taking just one pill, the deficiency symptoms disappeared. My B12 levels are now back to normal, and I take 5000 units once a week under the tongue. I highly recommend this to everyone.
Read More
7.5
Cognitive improvement
1 people found this helpful
Excellent contribution of vitamin B12! I have Hashimoto's thyroiditis, making it hard to absorb nutrients. Previously, I was anemic due to B12 deficiency, impacting my cognition. My endocrinologist advised me to take it every other day. Though I haven't repeated the tests yet, I feel an improvement in my ability to concentrate on reading and understanding content. The tablets are great in size, small, and sublingual with a mild sweet flavour.
Read More
7.5
Boosted energy levels
1 people found this helpful
Really made a difference! My physician identified that I was low in B12, so I tried several brands from both drugstores and health food stores. After trying Solgar, I noticed a significant increase in my energy levels. The sublingual nuggets dissolve rapidly, making them a great product, and I plan to continue using this brand.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
  • All Researches
7
Vitamin B12 ineffective alone
We explored how vitamin B12 might serve as a protective agent against food poisoning, particularly from pyrrolizidine alkaloids found in tansy ragwort. The study assessed various dietary supplements alongside vitamin B12, including butylated hydroxyanisole and cysteine, on rats exposed to these toxic compounds. While the combination of these agents did enhance the survival time of the rats significantly, the added vitamin B12 did not show any notable improvement in outcomes when used alone.

In examining our findings, it became clear that B12's contribution in isolation lacked evidence of effectiveness against PA poisoning. The results indicated that while certain combinations could be beneficial, vitamin B12 alone did not alter the susceptibility to the toxic effects observed from the chronic consumption of tansy ragwort. This highlights the need for further investigation into the role of B12 and how it interacts with other treatments.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Symptoms disappeared
1 people found this helpful
Best B12 for vegans and raw foodists! After switching to a vegan diet, I had a strong shortage of B12. Remarkably, after taking just one pill, the deficiency symptoms disappeared. My B12 levels are now back to normal, and I take 5000 units once a week under the tongue. I highly recommend this to everyone.
Read More
7.5
Cognitive improvement
1 people found this helpful
Excellent contribution of vitamin B12! I have Hashimoto's thyroiditis, making it hard to absorb nutrients. Previously, I was anemic due to B12 deficiency, impacting my cognition. My endocrinologist advised me to take it every other day. Though I haven't repeated the tests yet, I feel an improvement in my ability to concentrate on reading and understanding content. The tablets are great in size, small, and sublingual with a mild sweet flavour.
Read More
7.5
Boosted energy levels
1 people found this helpful
Really made a difference! My physician identified that I was low in B12, so I tried several brands from both drugstores and health food stores. After trying Solgar, I noticed a significant increase in my energy levels. The sublingual nuggets dissolve rapidly, making them a great product, and I plan to continue using this brand.
Read More

Frequently Asked Questions

9
Symptoms disappeared
1 people found this helpful
Best B12 for vegans and raw foodists! After switching to a vegan diet, I had a strong shortage of B12. Remarkably, after taking just one pill, the deficiency symptoms disappeared. My B12 levels are now back to normal, and I take 5000 units once a week under the tongue. I highly recommend this to everyone.
7.5
Cognitive improvement
1 people found this helpful
Excellent contribution of vitamin B12! I have Hashimoto's thyroiditis, making it hard to absorb nutrients. Previously, I was anemic due to B12 deficiency, impacting my cognition. My endocrinologist advised me to take it every other day. Though I haven't repeated the tests yet, I feel an improvement in my ability to concentrate on reading and understanding content. The tablets are great in size, small, and sublingual with a mild sweet flavour.
7.5
Boosted energy levels
1 people found this helpful
Really made a difference! My physician identified that I was low in B12, so I tried several brands from both drugstores and health food stores. After trying Solgar, I noticed a significant increase in my energy levels. The sublingual nuggets dissolve rapidly, making them a great product, and I plan to continue using this brand.
7
Vitamin B12 ineffective alone
We explored how vitamin B12 might serve as a protective agent against food poisoning, particularly from pyrrolizidine alkaloids found in tansy ragwort. The study assessed various dietary supplements alongside vitamin B12, including butylated hydroxyanisole and cysteine, on rats exposed to these toxic compounds. While the combination of these agents did enhance the survival time of the rats significantly, the added vitamin B12 did not show any notable improvement in outcomes when used alone.

In examining our findings, it became clear that B12's contribution in isolation lacked evidence of effectiveness against PA poisoning. The results indicated that while certain combinations could be beneficial, vitamin B12 alone did not alter the susceptibility to the toxic effects observed from the chronic consumption of tansy ragwort. This highlights the need for further investigation into the role of B12 and how it interacts with other treatments.

References

  1. Garrett BJ, Cheeke PR. Evaluation of amino acids, B vitamins and butylated hydroxyanisole as protective agents against pyrrolizidine alkaloid toxicity in rats. J Anim Sci. 1984;58:138.
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